Rent a Car in South Carolina

Whether you’re looking to relax on Myrtle Beach or explore the state’s rich history, South Carolina has something for everyone. Take a historical tour at Middleton Place, take the kids to the Joe Riley Waterfront Park in Charleston, or plan a remote getaway at Hilton Head Island.

The best part of vacation is the freedom to explore the area you’re staying in. No matter your adventure, a South Carolina car rental is the best way to reach your destinations. Choose Avis for a wide selection of affordable rental options at convenient rental locations throughout the state. Book your car rental in SC today. 

South Carolina’s Most Popular Cities


Myrtle Beach

Recommended Rental Cars in South Carolina

Intermediate Car

Are you looking to rent a car in South Carolina that’s more versatile? Book an intermediate car and get more space than a compact car while maintaining fuel efficiency.


Rent Now

Standard SUV

Standard SUVs are great for handling all of South Carolina terrain while being roomy enough for the whole family.


Rent Now


When are convertibles not the perfect car rental in South Carolina? Hop into one of our convertibles and let your hair down to experience winding roads and coastline boulevards in a new light.


Rent Now